An autoantibody inhibitory to glutamic acid decarboxylase in the neurodegenerative disorder Batten disease
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منابع مشابه
An autoantibody inhibitory to glutamic acid decarboxylase in the neurodegenerative disorder Batten disease.
Mutations in the CLN3 gene are responsible for the neurodegenerative disorder Batten disease; however, the molecular basis of this disease remains unknown. In studying a mouse model for Batten disease, we report the presence of an autoantibody to glutamic acid decarboxylase (GAD65) in cln3-knockout mice serum that associates with brain tissue but is not present in sera or brain of normal mice. ...
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ژورنال
عنوان ژورنال: Human Molecular Genetics
سال: 2002
ISSN: 1460-2083
DOI: 10.1093/hmg/11.12.1421